Focused Issue on Recent Advances in Rare Liver Diseases

Posted On 2019-06-25 15:27:51


This focused issue on “Recent Advances in Rare Liver Diseases” is edited by Dr. Luca Fabris, from Department of Molecular Medicine (DMM), University of Padua, Padua, Italy; and Dr. Mario Strazzabosco, from Department of Internal Medicine, Yale University, New Haven, CT, USA.

Dr. Luca Fabris got his PhD at University of Milan, Italy (1997), after a research program developed at University of Birmingham, UK (1995-96). In 2005, he was nominated assistant Professor at the University of Padua, School of Medicine. Currently, as associate Professor in Gastroenterology, he leads a laboratory of experimental Hepatology in the Department of Molecular Medicine, in the same University. Over the last 20 years, he has focused his scientific interests on topics related to pathophysiology of cholangiopathies, both of inflammatory and neoplastic origin, mainly devoted to liver cell biology studies. From 2012, he has been holding an appointment as adjunct Professor in the Yale University, CT, USA, where he is involved in the program of genetic biliary diseases and cancers.

Dr. Mario Strazzabosco was appointed Director and Clinical Program Leader of the Smilow Liver Cancer Program on January 1, 2017. With expertise in advanced hepatology, Dr. Strazzabosco is an expert in the care of patients with liver cancer. Dr. Strazzabosco returned to Yale after serving as the Founding Chief of the Section of Digestive Diseases, Chair of the Department of Surgery and Translational Medicine, and Vice President of the School of Medicine at the University of Milan. He is internationally known for his work in Hepatology and Liver Transplantation, previously served as Medical Director of Hepatology at Yale, is a recipient of NIH funding, and is a member of several scientific societies in Europe and in the United States. Dr. Strazzabosco holds an appointment as Professor of Medicine (Digestive Diseases) at Yale School of Medicine and as Deputy Director of the Yale Liver Center.

Focused issue outline:
  1. Rare Disease in Hepatology
    Luca Fabris, Department of Molecular Medicine, University of Padua, Padua, Italy
    Mario Strazzabosco, Department of Internal Medicine, Yale University, New Haven, CT, USA
  2. New Opportunities for Diagnosis and Disease Modeling (genomics, proteomics, lipidomics, metabolomics, iPSC and organoids)
    Romina Fiorotto, Department of Internal Medicine, Yale University, New Haven, CT, USA
  3. Liver Pathology 2.0 (Maldi, etc)
    Dhanpat Jain, Department of Pathology, Yale University, New Haven, CT, USA
  4. Iron Metabolism Defects
    Alberto Piperno, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
  5. Wilson Disease
    Michael L. Schilsky, Section of Digestive Diseases, Department of Medicine and Surgery, Yale University School of Medicine, New Haven, CT, USA
  6. Alagille Syndrome and Non-Syndromic Paucity of Intrahepatic Bile Ducts
    Kathleen M. Loomes, Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital, Philadelphia, PA, USA
  7. Disorders of Bilirubin Metabolism
    Jayanta Roy Chowdhury, Division of Gastroenterology and Liver Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
  8. Alpha-1 Antitrypsin Deficiency (AATD)
    Jeffrey Teckman , Department of Pediatrics, Saint Louis University School of Medicine, 1465 S. Grand Blvd., Saint Louis, MO, USA
  9. Hepatic Porphyrias
    Bruce Wang, Division of Gastroenterology, Department of Medicine, University of California San Francisco, USA
  10. Giant Cell Hepatitis
    Giuseppe Maggiore, Department of Pediatrics and Division of Pediatric Gastroenterology and Hepatology, University Hospital Santa Chiara, Pisa, Italy
  11. Fibropolycystic Liver Diseases
    Carlo Spirli, Department of Internal Medicine, Yale University, New Haven, CT, USA
  12. Rare Liver Tumors
    Diego F. Calvisi, Institute of Pathology, University of Regensburg, Regensburg, Germany
  13. Liver Transplantation for Rare Liver Diseases
    Umberto Cillo, Enrico Gringeri and Alessandro Vitale, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy
  14. Genome Editing Technologies to Treat Rare Diseases
    Giorgio Palù, Marta Trevisan, Department of Molecular Medicine, University of Padua, Padua, Italy
  15. Undiagnosed Liver Diseases
    Silvia Villarinho, Department of Internal Medicine, Yale University, New Haven, CT, USA
    Theo Heller, Translational Hepatology Unit, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA