TY - JOUR AU - Zhang, Xiaocen AU - Modayil, Rani AU - Criscitelli, Theresa AU - Stavropoulos, Stavros N. PY - 2019 TI - Endoscopic resection for subepithelial lesions—pure endoscopic full-thickness resection and submucosal tunneling endoscopic resection JF - Translational Gastroenterology and Hepatology; Vol 4 (May 2019): Translational Gastroenterology and Hepatology Y2 - 2019 KW - N2 - Endoscopic full-thickness resection (EFTR) and submucosal tunneling endoscopic resection (STER) are the frontier of therapeutic endoscopic. These two methods rely on the skillset and equipment of endoscopic submucosal dissection (ESD) while going beyond the boundaries of the gastrointestinal lumen. They are both representatives of natural orifice transluminal endoscopic surgery, with STER being a direct off-shoot of peroral endoscopic myotomy (POEM). Both techniques are designed for the removal of gastrointestinal tumors originating from the muscularis propria but tend to be used in different organs and come with respective challenges. In this review we will go over the history, indication, technique and literature of these two techniques. UR - https://tgh.amegroups.org/article/view/5080