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RAINFALL before RAINBOW—an illusion or reality?

	author = {Kohei Shitara},
	title = {RAINFALL before RAINBOW—an illusion or reality?},
	journal = {Translational Gastroenterology and Hepatology},
	volume = {2},
	number = {3},
	year = {2017},
	keywords = {},
	abstract = {Combination with fluoropyrimidines and platinum-based agents have been used as first-line therapy for metastatic gastric/gastroesophageal junction cancer (GC) resulting in a median progression-free survival (PFS) of 5–6 months and a median overall survival (OS) of 10–15 months. Trastuzumab, a monoclonal antibody against human epidermal growth factor receptor 2 (HER2), significantly improved the OS of HER2-positive GC patients, which consists of around 15% of patients (1). However, other randomized studies failed to show benefits of several molecular targeting agents for GC in first-line (2-7), thus development of more effective combination is important.},
	url = {}