%0 Journal Article %T Liver resection for hepatocellular carcinoma ≥5 cm %A Ettorre, Giuseppe Maria %A Levi Sandri, Giovanni Battista %A Colasanti, Marco %A Mascianà, Gianluca %A de Werra, Edoardo %A Santoro, Roberto %A Lepiane, Pasquale %A Montalbano, Marzia %A Antonini, Mario %A Vennarecci, Giovanni %J Translational Gastroenterology and Hepatology %D 2017 %B 2017 %9 %! Liver resection for hepatocellular carcinoma ≥5 cm %K %X Background: Management of hepatocellular carcinoma (HCC) larger than 5 cm is still debated. The aim of our study was to compare morbidity and mortality after the surgical resection of HCC according to the nodule size. Methods: Since 2001, 429 liver resections for HCC were performed in our institution. We divided the cohort into two groups, 88 patients in group 1 patients with HCC diameter from 5 to 10 cm and 39 patients in group 2 with HCC diameter ≥10 cm. Results: In 30.7% of cases in the first group and in 35.9% of cases in the second group the HCC grew into a healthy liver. A major liver resection was performed in 36.3% of cases in group 1 vs . 66.6% in group 2 (P=0.001). In two cases for the first group and in ten cases in the second group a laparoscopic approach was performed. Median operative time was higher in group 2 (P=0.001). The median post-operative hospital stay was similar in the two groups (P=0.897). The post-operative morbidity was not different between the two groups (P=0.595). Conclusions: The tumour size does not contraindicate a surgical resection of HCC even in patient with HCC ≥10 cm. %U https://tgh.amegroups.org/article/view/3714 %V 2 %P %@ 2415-1289