Alcohol-associated liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are commonest causes of chronic liver disease. In spite of different risk factor, they share common spectrum of fatty liver/steatosis, steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. However, these two diseases are different on many aspects. With the progress made over the last decade, Translational Gastroenterology and Hepatology feels the need for reviewing the latest updates and identify unmet needs with future prospects on ALD and NAFLD. It is my privilege to guest edit this focused issue, with contributions on various aspects by experts in the respective field.
Similarities and differences between non-alcoholic fatty liver disease (NAFLD) & alcohol-associated liver disease (ALD)
Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD)
Clinical presentation of alcoholic liver disease and non-alcoholic fatty liver disease: spectrum and diagnosis
Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations
Hepatocellular carcinoma in alcoholic and non-alcoholic fatty liver disease—one of a kind or two different enemies?
Basic science to clinical trials in non-alcoholic fatty liver disease and alcohol-related liver disease: collaboration with industry
The series “Non-alcoholic Fatty Liver Disease and Alcoholic Liver Disease” was commissioned by the editorial office, Translational Gastroenterology and Hepatology without any sponsorship or funding. Ashwani K. Singal served as the unpaid Guest Editor for the series.