Article Abstract

Lymph node metastases in early gastric cancer, when the East and the West come to terms

Authors: Mohamed M. Abdelfatah, Mohamed O. Othman


Endoscopic resection of early gastric cancer (EGC) is limited by the risk of lymph node metastasis (LNM). In general, resection of small (less than 2 cm) differentiated EGC which is limited to the mucosa is deemed safe due to negligible risk of lymph node metastasis. Expanding endoscopic resection beyond this criterion has been a matter of debate. In a land mark study by Gotoda et al., the risk of LNM for mucosal differentiated lesions without ulceration, irrespective of size, mucosal differentiated ulcerated lesions ≤2 cm, and poorly differentiated lesions ≤3 cm was 0% (1).